## STEP 1

MIX

ORANGE CAP UP
SHAKE HARD UP AND
DOWN FOR AT LEAST 15
SECONDS TO DISPERSE
MEDICINE EVENLY1
COMPLETE

## STEP 2

UNLOCK

ORANGE CAP UP
TWIST KNOB FROM LOCK TO UNLOCK1
ORANGE CAP UP
TWIST KNOB FROM LOCK
TO UNLOCK1
CLICK
COMPLETE

## STEP 3

UNSCREW

ORANGE CAP UP
TWIST ORANGE CAP COUNTERCLOCKWISE1
DO NOT PULL
COMPLETE

## STEP 4

INJECT

IMMEDIATELY INJECT BY PUSHING
AGAINST THE SKIN AND HOLDING FOR
15 SECONDS TO ENSURE A FULL DOSE 1
INJECTION STARTS WHEN AUDIBLE
CLICK IS HEARD1
IMMEDIATELY INJECT BY
PUSHING AGAINST THE
SKIN AND HOLDING FOR
15 SECONDS TO ENSURE
A FULL DOSE 1
INJECTION STARTS WHEN
AUDIBLE CLICK IS HEARD1

VIEW INJECTION SITES

CLICK
DONE - IT'S THAT SIMPLE!2*
DONE - IT'S THAT SIMPLE!2*

EXPLORE DEVICE

VIEW SAVINGS CARD

## WELCOME TO THE BYDUREON BCISE

# 3D DEVICE SIMULATOR

Learn to use once-weekly BYDUREON BCise. BYDUREON BCise is for adults with T2D along with
diet and exercise uncontrolled on their current treatment, who need a GLP-1 RA to improve glycemic control.1
Learn to use once-weekly BYDUREON BCise.
BYDUREON BCise is for adults with T2D along with
diet and exercise uncontrolled on their current treatment,
who need a GLP-1 RA to improve glycemic control.1

START

1

## EXPLORE

# BYDUREON BCISE IN 3D

Swipe the screen to rotate the device. Pinch and expand to zoom in and out.

# SINGLE DOSE AUTOINJECTOR

## BYDUREON BCise

# SAVINGS PROGRAM

BYDUREON BCise is the ONLY GLP-1 RA with a $0* savings offer,
for eligible patients.

GET SAVINGS CARD

*SEE ELIGIBILITY REQUIREMENTS HERE. RESTRICTIONS APPLY.

CLICK & DRAG UP OR DOWN
ON THE DEVICE TO MIX

SWIPE UP OR DOWN
ON THE DEVICE TO MIX

SUCCESS = MEDICINE IS MIXED EVENLY AND CLOUDY
IN COLOR. YOU DO NOT SEE ANY MEDICINE ALONG
THE SIDES, BOTTOM OR TOP.1
SUCCESS = MEDICINE IS MIXED
EVENLY AND CLOUDY IN COLOR. YOU
DO NOT SEE ANY MEDICINE ALONG
THE SIDES, BOTTOM OR TOP.1
DO NOT PROCEED TO THE NEXT STEP UNTIL
MEDICINE IS WELL-MIXED.1
DO NOT PROCEED TO THE NEXT STEP
UNTIL
MEDICINE IS WELL-MIXED.1

CONTINUE
TO STEP 2

CLICK & DRAG LEFT ON
THE DEVICE TO UNLOCK

SWIPE LEFT ON
THE DEVICE TO UNLOCK

SUCCESS = AUDIBLE CLICK SOUND1
SUCCESS = AUDIBLE CLICK
SOUND1

CONTINUE
TO STEP 3

CLICK & DRAG RIGHT ON THE
DEVICE TO UNSCREW CAP

SWIPE RIGHT ON THE
DEVICE TO UNSCREW CAP

SUCCESS = ORANGE CAP LIFTS OFF WITHOUT
EFFORT AND GREEN SHIELD POPS UP1
SUCCESS = ORANGE CAP
LIFTS OFF WITHOUT
EFFORT AND GREEN
SHIELD POPS UP1

CONTINUE
TO STEP 4

CLICK & DRAG DOWN
ON THE DEVICE
TO INJECT

SWIPE DOWN
ON THE DEVICE
TO INJECT

SUCCESS = ORANGE ROD APPEARS IN
WINDOW, PLUNGER STOPS MOVING AND
DEVICE HAS BEEN HELD FIRMLY AGAINST
SKIN FOR FULL 15 SECONDS1
SUCCESS = ORANGE ROD
APPEARS IN WINDOW,
PLUNGER STOPS MOVING
AND DEVICE HAS BEEN
HELD FIRMLY AGAINST
SKIN FOR FULL 15
SECONDS1

# INJECTION SITES

Weekly injection may use same body part, with new injection site1

# INSTRUCTIONS OVERVIEW

For complete instructions, please see Instructions for Use.
MAX
Shake up and down
for at least 15 seconds
until well mixed1
UNLOCK
Turn clockwise
to unlock1
UNSCREW
Unscrew orange cap
counterclockwise1
INJECT
Inject immediately and
hold for 15 seconds to
get full dose1

# HOW SUPPLIED, STORAGE & HANDLING1

# HOW SUPPLIED,
STORAGE & HANDLING1

BYDUREON Bcise comes in a box with a 4-week supply and full Instructions for Use.
BYDUREON Bcise should be stored flat in the refrigerator between 36°F and 46°F
(2°C and 8°C). Protect from light.
BYDUREON Bcise may be kept at room temperature, not to exceed 86°F (30°C),
for up to 4 weeks.
BYDUREON Bcise comes in a box with a 4-week supply and
full Instructions for Use.
BYDUREON Bcise should be stored flat in the refrigerator
between 36°F and 46°F (2°C and 8°C). Protect from light.
BYDUREON Bcise may be kept at room temperature, not to
exceed 86°F (30°C), for up to 4 weeks.

# DISPOSAL TIPS

- Do NOT dispose in household trash1
- Use an FDA-cleared sharps container1
- If not available, use heavy-duty plastic container
  with a tight-fitting, puncture-resistant lid1
- Properly label as hazardous waste1
- Follow all state and local disposal laws1

Visit www.safeneedledisposal.org for more information.

# REFERENCES

1. BYDUREON BCise® ([exenatide extended-release] injectable suspension)
   [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020.
2. Data on file, REF-14053, AstraZeneca Pharmaceuticals LP.

CLOSE

STEP 1

MIX

STEP 2

UNLOCK

STEP 3

UNSCREW

STEP 4

INJECT

EXPLORE

SAVINGS CARD